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284030

CRISPR in dentistry: A boon or bane

Article

Last updated: 04 Jan 2025

Subjects

-

Tags

Microbial genetics and Proteomics

Abstract

Background: Clustered Regularly Inter Spaced Palindromic Repeats (CRISPR) is programmable protein that can change the genome's content, remove it, and switch it on and off. This cutting-edge technology offers a wide range of uses and has the potential to change the future of oral health. Because of its efficacy and precision, the CRISPR-associated protein 9 (Cas9) genome editing technology could be a promising therapeutic tool in the treatment of oral cancer. It quickly changes the genetic makeup of cell lines, organs, and animals. As a result, gene editing has expanded to include genome-wide screening for both loss and augmentation of function. The CRISPR-Cas9 genome editing method and its uses in dentistry have been summarised in this study.

DOI

10.21608/mid.2023.188121.1453

Keywords

Oral Diseases, CRISPR, Cas9, Genome editing, dentistry

Authors

First Name

Mirna

Last Name

Garhnayak

MiddleName

-

Affiliation

Professor, Department of Prosthodontics and Crown and Bridge, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be University), Bhubaneswar 751003, Odisha, India.

Email

mirnagarhnayak@gmail.com

City

Bhubaneswar

Orcid

-

First Name

Shakti

Last Name

Rath

MiddleName

-

Affiliation

Central Research Laboratory, Institute of Dental Sciences, Siksha O Anusandhan Deemed to be University, Bhubaneswar, Odisha

Email

dr.shaktirath@gmail.com

City

Bhubaneswar

Orcid

-

First Name

Loknath

Last Name

Garhnayak

MiddleName

-

Affiliation

Professor, Department of Prosthodontics and Crown and Bridge, SCB Dental College and Hospital, Cuttack 753007, Odisha, India

Email

loknathgarhnayak@gmail.com

City

Cuttack

Orcid

-

First Name

Sangram

Last Name

Panda

MiddleName

-

Affiliation

Professor, Department of Prosthodontics and Crown and Bridge, Institute of Dental Sciences, Siksha O Anusandhan (Deemed to be University), Bhubaneswar 751003, Odisha, India

Email

sangrampanda@soa.ac.in

City

Bhubaneswar

Orcid

-

Volume

4

Article Issue

4

Related Issue

43799

Issue Date

2023-11-01

Receive Date

2023-01-17

Publish Date

2023-11-01

Page Start

1,178

Page End

1,182

Print ISSN

2682-4132

Online ISSN

2682-4140

Link

https://mid.journals.ekb.eg/article_284030.html

Detail API

https://mid.journals.ekb.eg/service?article_code=284030

Order

15

Type

Mini-review article

Type Code

1,162

Publication Type

Journal

Publication Title

Microbes and Infectious Diseases

Publication Link

https://mid.journals.ekb.eg/

MainTitle

CRISPR in dentistry: A boon or bane

Details

Type

Article

Created At

25 Dec 2024