Background: SARS-CoV-2 which causes COVID-19 can infect people with moderate to severe illnesses. In the months following the pandemic's initial detection in China in December 2019, it has quickly spread over the globe. The virus has continued to be prevalent in numerous countries with different mutated strains associated with variable degrees of clinical symptoms despite significant attempts to limit the disease. A coordinated strategy incorporating precise epidemiology, surveillance, prophylaxis, and surveillance is necessary to limit this pandemic. Therefore, accurate diagnosis utilizing quick technology is essential. The precise and timely diagnosis of SARS-CoV-2 is crucial for the efficient care and prevention of COVID-19 patients as well as to stop the transmission of the disease in light of the rising incidence of COVID-19 cases. The various diagnostic techniques for the diagnosis of COVID-19 infection in both clinical and research settings are described in the current review. This article specifically describes the technical and instrumental aspects of the diagnostic techniques employed. The diagnostic methods are all covered in updated and comprehensive detail.