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269610

Co-infection and associated risk factors of herpes simplex virus type-1 and human immunodeficiency virus among patients attending Faith Alive Foundation Hospital Jos, North Centr

Article

Last updated: 25 Dec 2024

OverviewSimilar Items

Subjects

-

Tags

Infectious diseases

Abstract

Background: Studies have reported that Genital herpes is of high public health implications in immuno-compromised individuals. Aim: The study seeks to determine how common herpes simplex virus -1 (HSV-1) infections are among human immunodeficiency virus (HIV) carriers and identify associated risk factors. Methods: Eighty-seven (87) apparently healthy subjects were tested for HSV-1 and HIV-1 using an Enzyme-Linked Immunosorbent Assay (ELISA) test Kit (Clinotech, Canada, USA), containing HSV-1 type-specific glycoprotein; Determine Kit (Inverness Medicom, Japan) and UniGold Kit (Trinity Biotech, Bray, Ireland), containing recombinant antigens. Results: Of 87 sera, 76(87.4%), and 30(34.5%) were seropositive for HSV-1 and HIV respectively while the co-infection seroprevalence rate of both viruses was 26(29.9%). The co-infection seroprevalence rate of HSV-1 and HIV-1 was highest in the age group ≥45 years (47.4%) while the age group 15-24 years had the lowest co-infection seroprevalence rate of 14.3% (p < /em>>0.05). Women had a higher co-infection seroprevalence rate of 34.0% than men (24.3%). Of all the socio-demographics assessed, only the level of education was significantly associated with the prevalence of HIV and HSV-1/HIV co-infection respectively (p = 0.003; 0.001). Conclusions: The present study showed that HSV-1 infections are common among HIV carriers and HSV-1 is endemic in the study population as all age groups were affected. This finding underscores the need for further research to understand the interactions between HSV-1 and HIV to provide effective methods of reducing the infection burden.

DOI

10.21608/mid.2022.168774.1399

Keywords

Herpes simplex Virus type 1, HIV, co-infection, Jos, Nigeria

Authors

First Name

Yusuf

Last Name

Agabi

MiddleName

Amuda

Affiliation

Department of Microbiology, Faculty of Natural Science, University of Jos, Nigeria

Email

yusufagabi@gmail.com

City

-

Orcid

https://orcid.org/00

First Name

Adebayo

Last Name

Ogundele

MiddleName

Samson

Affiliation

Department of Microbiology, Faculty of Natural Sciences, University of Jos, Nigeria

Email

samsonogundele@gmail.com

City

Jos

Orcid

-

First Name

Jesse

Last Name

Ishaya

MiddleName

-

Affiliation

Kaduna Polytechnic, Tudun Wada, P.M.B. 2021, Kaduna, Nigeria

Email

isahaj@gmail.com

City

Kaduan

Orcid

-

First Name

Alhassan

Last Name

Damter

MiddleName

Fwangmun

Affiliation

Dermatophylosis Research Division, NVRI Vom, PMB 01, Vom

Email

fatso@gmail.com

City

Jos

Orcid

-

First Name

John

Last Name

Mawak

MiddleName

Danjuma

Affiliation

Department of Microbiology, Faculty of Natural Sciences, University of Jos, Jos, Plateau State, Nigeria

Email

mawakj@unijos.edu.ng

City

Jos

Orcid

-

First Name

John

Last Name

Egbere

MiddleName

Otumala

Affiliation

Department of Microbiology, Faculty of Natural Sciences, University of Jos, Nigeria

Email

egbereo@yahoo.com

City

Jos

Orcid

-

First Name

Hashimu

Last Name

Zakari

MiddleName

-

Affiliation

Department of Microbiology, Faculty of Natural Sciences, University of Jos, Jos, Plateau State, Nigeria

Email

hashyz1000@yahoo.com

City

Jos

Orcid

-

First Name

Murna

Last Name

Ali

MiddleName

-

Affiliation

Department of Microbiology, Faculty of Natural Sciences, University of Jos, Nigeria

Email

murnaa@gmail.com

City

Jos

Orcid

-

First Name

Marycelin

Last Name

Baba

MiddleName

Mandu

Affiliation

Department of Medical Laboratory Sciences, College of Medical Sciences, University of Maiduguri, P.M.B. 1069, Maiduguri, Nigeria

Email

marycelinm@gmail.com

City

Maiduguri

Orcid

-

Volume

4

Article Issue

2

Related Issue

40831

Issue Date

2023-05-01

Receive Date

2022-10-14

Publish Date

2023-05-01

Page Start

428

Page End

435

Print ISSN

2682-4132

Online ISSN

2682-4140

Article File

MID_Volume 4_Issue 2_Pages 428-435.pdf

PDF . 465.7kB

Link

https://mid.journals.ekb.eg/article_269610.html

Detail API

https://mid.journals.ekb.eg/service?article_code=269610

Order

12

Type

Original Article

Type Code

1,157

Publication Type

Journal

Publication Title

Microbes and Infectious Diseases

Publication Link

https://mid.journals.ekb.eg/

MainTitle

Co-infection and associated risk factors of herpes simplex virus type-1 and human immunodeficiency virus among patients attending Faith Alive Foundation Hospital Jos, North Central Nigeria

Details

Type

Article

Created At

25 Dec 2024