201076

Virulence factors in <i>Pseudomonas aeruginosa</i>: The arms race between bacteria and humans

Article

Last updated: 04 Jan 2025

Subjects

-

Tags

Medical bacteriology

Abstract

Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative, motile bacillus that can grow at 42°C as well as 37°C in aerobic circumstances. It also tests positive for oxidase and catalase enzymes.The bacteria may be found in a variety of habitats, including water and soil.  It is also considered an opportunistic human pathogen which has the capacity to causes infection especially in individuals with immunocompromised systemand also can be present in hospital climate.
P. aeruginosa has several virulence factors that play a role in pathogenesis in the host, including type IV pili, which are found near the cell poleand flagella.It also releases exopolysaccharide alginate, which is utilized to build biofilm. Lipases and phospholipases, which target lipids in the surfactant and host cell membranes, are further pathogenic agents of the bacteria.As well as exoenzymes S, T, U, and Y. P. aeruginosa also produces extracellular virulence factors such as elastase, toxin A, rhamnolipids, lipopolysaccharide (LPS), and protease. These factors may be shared by other pathogens and may contribute directly or indirectly in resistance to multiple antibacterial agents.

DOI

10.21608/mid.2021.99954.1202

Keywords

Virulence factors, P. aeruginosa, Bacteria, Antimicrobial agents

Authors

First Name

Falah

Last Name

AL-Khikani

MiddleName

-

Affiliation

Medical Laboratory Technology Department, College of Medical Technology, The Islamic University, Najaf, Iraq

Email

falahgh38@gmail.com

City

-

Orcid

0000-0002-8890-7090

Volume

4

Article Issue

1

Related Issue

39092

Issue Date

2023-02-01

Receive Date

2021-09-07

Publish Date

2023-02-01

Page Start

94

Page End

96

Print ISSN

2682-4132

Online ISSN

2682-4140

Link

https://mid.journals.ekb.eg/article_201076.html

Detail API

https://mid.journals.ekb.eg/service?article_code=201076

Order

14

Type

Correspondence

Type Code

1,163

Publication Type

Journal

Publication Title

Microbes and Infectious Diseases

Publication Link

https://mid.journals.ekb.eg/

MainTitle

Virulence factors in <i>Pseudomonas aeruginosa</i>: The arms race between bacteria and humans

Details

Type

Article

Created At

25 Dec 2024