Crustacean decapods form a significant and important component of commercial fisheries in the region of the Suez Gulf. Current investigation was carried out mainly to examine the reproductive system of blue swimmer crab's (Portunus pelagicus) males and females. Samples of Blue swimmer crab were collected from the Suez Gulf. Histological sections were applied to confirm the morphological stages of blue crab's males and females' gonads. The results obtained showed that the reproductive system of both males and females' gonads in P. pelagicus was like that of other decapod crustaceans. Male of Portunus pelagicus is bilaterally symmetrical, consist of a pair of ejaculatory ducts internally and a pair of vas deferentia. Vas deferentia consist of three parts, the Anterior (AVD), the Median (MVD), and the Posterior (PVD). Also, the investigation of the ovaries indicated that the females could spawn throughout the year. The results suggest that local management of the blue swimming crab fishery recommend setting closed seasons to preserve juvenile crabs of this species, protecting areas of spawning and nursery grounds from illegal fishing, pollution, and habitat loss.