Azo dyes, such as reactive black 5 (RB5), are extensively employed in the textile industry due to their stabilities and simple dyeing procedures. About 50% of the amount of RB5 used is lost and discharged into nearby aquatic systems, causing chronic and acute toxicity. Therefore, it is necessary to treat the contaminated effluents before releasing them into the surroundings. The study synthesized SiO2&GO-doped titanium dioxide nanofibers with highly photocatalytic activity, utilizing the electrospinning method followed by calcination. Additionally, the study used SEM, FESEM, EDX, XRD, TEM analysis, and UV-vis data to characterize the morphology and the structures of the synthesized nanofibers. The photocatalytic activities of the produced nanofibers were examined for the removal of the reactive black 5 and reactive orange 16. The results showed that SiO2&GO-doped titanium dioxide nanofibers could eliminate 86 % of the reactive black within 2 h compared to 19 % removal of the reactive black 5 when using the pristine TiO2 nanofibers. Moreover, the photocatalysts could be reused many times without any obvious changes in their stability and activity, suggesting a potential application for wastewater treatment.