The subterranean termite, Psammotermes hypostoma Desenex is a significant pest in Qena governorate, Egypt. With regard to P. hypostoma pest, we determined the toxicity of four essential oils: caraway, cinnamon, neem, and anise. The bioassay was conducted under laboratory conditions by used five concentrations [ 62.5, 31.25, 15.62, 7.8 and 3.90 ppm] from each oil. After 24h from treatment the results showed the LC₅₀ values of caraway, anise, neem and cinnamon oils were 5.79, 7.3, 11.86 and 23.07 ppm, respectively, while toxicity index were 100, 78.72, 48.82 and 18.94 respectively. These results showed that the most effective one was caraway oil on the other hand the least effective one was cinnamon oil. The neem oil and anise oil were located in between. We recommend that these essential oils be included in the integrated termite control programs as an environmentally safe and healthy means for humans compared with comical pesticides