The current research aimed to verify the effectiveness of the story of our amazing immune system in simplifying some concepts of the immune system for kindergarten children. Where the research was applied to a sample consisting of (50 children) of children enrolled in the second level of Muhammad Abu Zaid Al-Saidi School affiliated to the West Al-Mahalla Educational Administration, and the researcher followed the semi-experimental approach and adopted the experimental design with one group (pre and post application on one experimental group), The research tools were represented by the researcher preparing a picture story entitled "Our Amazing Immune System" in order to involve the child in cognitive processes through which the researcher simplifies some concepts of the immune system, and preparing: a battery for assessing the knowledge of some concepts of the immune system in kindergarten children, and the (T) test was used for related samples in analyzing the data quantitatively, the results revealed that there were statistically significant differences at the level of significance (α≤ 0.05) between the mean scores of the children of the experimental group for the pre and post measurements on the battery of assessing the knowledge of some concepts of the immune system for the kindergarten child, which indicates the effectiveness of the story used in simplifying some concepts of the immune system of a kindergarten child.