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397261

IN VITRO STUDY ON THE ANTIPARASITIC EFFECT OF OMEPRAZOLE ON CRYPTOSPORIDIUM PARVUM

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Last updated: 25 Dec 2024

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Abstract

Cryptosporidiosis is an important zoonotic diarrheal disease of worldwide distribution in man 
animals as well water canals, causing about one million deaths annually. This study investigated 
the anti-parasitic and anti-inflammatory effects of omeprazole versus nitazoxanide and as a 
combined therapy to treat Cryptosporidium parvum infection in tissue culture. Histopathological 
and SEM examinations on infected tissue cultures evaluated treatment. 
The results showed marked treated and inflammation improvement with omeprazole over nita
zoxanide combined treatment as indicated by histopathological and SEM studies.

DOI

10.21608/jesp.2024.397261

Keywords

cryptosporidiosis, culture, Omeprazole, Nitazoxanide Histopathology, SEM

Authors

First Name

MAI

Last Name

ATALLAH

MiddleName

A.

Affiliation

Department of Medical Parasitology, Faculty of Medi cine, Tanta University, Egypt

Email

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City

-

Orcid

-

First Name

SAMY

Last Name

EL-KOWRANY

MiddleName

I.

Affiliation

Department of Medical Parasitology, Faculty of Medi cine, Tanta University, Egypt

Email

-

City

-

Orcid

-

First Name

OMAYMA

Last Name

AFIFI

MiddleName

K.

Affiliation

Department of Histology, Faculty of Medi cine, Tanta University, Egypt

Email

-

City

-

Orcid

-

First Name

HEBA

Last Name

ELKALINY

MiddleName

H.

Affiliation

Department of Histology and Anatomy, Mutah University, Mutah, Jordan

Email

-

City

-

Orcid

-

First Name

SALWA

Last Name

YOUNIS

MiddleName

S.

Affiliation

Department of Medical Parasitology Faculty of Medicine, Alexandria University, Egypt

Email

-

City

-

Orcid

-

First Name

GHADA

Last Name

GAMEA

MiddleName

A.

Affiliation

Department of Medical Parasitology, Faculty of Medi cine, Tanta University, Egypt

Email

-

City

-

Orcid

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Volume

54

Article Issue

3

Related Issue

52146

Issue Date

2024-12-01

Receive Date

2024-12-16

Publish Date

2024-12-01

Page Start

453

Page End

458

Print ISSN

1110-0583

Online ISSN

2090-2549

Article File

JESP_Volume 54_Issue 3_Pages 453-458.pdf

PDF . 3.6MB

Link

https://jesp.journals.ekb.eg/article_397261.html

Detail API

https://jesp.journals.ekb.eg/service?article_code=397261

Order

14

Type

Original Article

Type Code

1,127

Publication Type

Journal

Publication Title

Journal of the Egyptian Society of Parasitology

Publication Link

https://jesp.journals.ekb.eg/

MainTitle

IN VITRO STUDY ON THE ANTIPARASITIC EFFECT OF OMEPRAZOLE ON CRYPTOSPORIDIUM PARVUM

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Article

Created At

25 Dec 2024