Cryptosporidium is one of the major causes of parasitic diarrhea all over the world. Both animals
and humans are impacted. The fecal-oral pathway encompasses the consumption of infected water
or food, as well as the intake of oocysts following direct touch with infected humans or animals.
There is a lack of treatment alternatives for cryptosporidiosis sufferers. Nitazoxanide is the
only one that has been approved by the Food and Drug Administration (FDA) as a therapy for
cryptosporidiosis. Colorectal cancers were linked to Cryptosporidium infections. Some diseases,
including hematological malignancies and liver cancer were also be linked to infections with
Cryptosporidium spp. Infection with Cryptosporidium leads to hyperproliferation, invasion, and
resistance to apoptosis and immune responses, via influencing host cellular pathways. While the
exact processes that lead to Cryptosporidium-induced intestinal neoplasia remain a mystery, it is
evident that they are complex and involve both the parasite and the host. Cancer is the leading
cause of death and disability is colon cancer.