parental separation. Harder induction, higher postoperative pain, emerging agitation, and possibly
postoperative behavioral and psychological problems can result from untreated anxiety.
This study aimed to compare intranasal dexmedetomidine (DEX) 2 μg/kg vs. 3μg/kg for children
undergoing dental surgery. This randomized double-blinded study involved 80 children
aged 2 to 10 years old of both sexes, planned for dental surgery. They were allocated into two
groups according to DEX intranasal dose given 30 minutes before general anesthesia (GA) induction,
GI: 2μg/kg and GII: 3μg/kg. IV cannulation was done before the GA induction.
The results showed that GII had a significantly better parental separation anxiety scale, Ramsay
sedation score, and IV cannula acceptance score than GI (P <0.001), without significant
difference as to parents' satisfaction score.