Inflammatory bowel disease (IBD) is a group of chronic relapsing inflammatory conditions of
the gastrointestinal tract. Inflammatory bowel disease has a substantial impact on quality of life.
It causes considerable personal, emotional, and social burdens. The impact of IBD on quality of
life places a significant burden on the patient and caregivers. The study assessed the impact of
inflammatory bowel disease and disease activity on quality of life of the patients.
This cross-section study was conducted on 88 patients with inflammatory bowel disease who
attended the IBD Clinic, Ain Shams University Hospitals. An informed consent was obtained
from each patient. All patients were subjected to clinical assessment, laboratory investigations,
colonoscopy, assessment of disease activity and assessment of quality of life using PCASEE
score.
The eighty-eight inflammatory bowel disease patients were divided into: G1: (CD) Crohn's
disease group 40 (45.5%) patients, and G2: ulcerative colitis (UC) group 48 (54.5%) patients.
They were 39 (44.3%) males and 49 (55.7 %) females, with ages ranged between 19 and 52
years old (mean 33).
The result showed negative significant correlation between clinical and endoscopic activity in
UC group measured by simple clinical colitis activity index and Mayo score respectively and
quality of life scores in the patients with P <0.001. In CD, there was negative significant correlation
between quality of life and clinical disease activity measured by Crohn's disease activity
index with P <0.001, but without endoscopic activity. There was no significant effect of inflammatory
bowel disease on quality of life of the patients especially during disease activity.