: Nowadays, E learning can be used along with traditional learning methods as a result of internet networks infrastructure development and available access to the most of students. This study aimed to compare students' responses and satisfaction regarding online, blended and traditional learning methods in relation to orthodontic knowledge and skills acquired for undergraduate students. Materials and Methods: An online survey was done among 262 students studying in Ahram Canadian University. The students were divided into 3 groups, where Group I represented the traditional method of teaching, Group II represented the online method and Group III, the blended method of teaching. A questionnaire including 14 questions was filled with students' opinions regarding different teaching methods. Then the data were collected and analyzed. Simple descriptive statistics was used to compare questionnaire responses for the whole sample and T-independent and Mann-Whitney tests to compare the 3 groups. Results: The results showed that there was no significant difference between the 3 groups in students' opinions regarding different teaching methods. The traditional teaching method group was satisfied with the way traditional lectures were conducted before the covid-19 pandemic. In the online teaching method group, most of the students agreed that lecture recordings during online classes were beneficial for self-study. While, in the blended teaching method group, most of the students agreed that regarding the lectures, they preferred a combination of traditional and online learning. Conclusion: The blended learning was the most preferable method for teaching orthodontics for undergraduate dental students.