Many people consider antibiotic treatment to be one of the most successful medical interventions ever developed. They have been able to treat bacterial diseases in humans, animals, and, to a lesser extent, plants, resulting in millions of lives being saved. They have demonstrated their efficacy in a variety of applications, such as food preservation, animal nutrition, and others. In addition to their notoriety as pathogens, bacteria are also the primary and most important source of antibiotics. Antibiotics were first discovered in bacteria. Microbes such as fungi, bacteria, and actinomycetes make antibiotics on their own to protect themselves from other microbes that may be in their environment. Soil microorganisms employ these adaptive strategies to live and reproduce in a wide variety of biotic and abiotic environments. Therefore, it is not surprising that bacteria can adapt to evade antibiotic elimination or develop resistance to the medicines they produce. Due to the growing need to fight diseases and stop the exponential spread of antibiotic resistance in the ever-changing microbial family, antibiotic research and production have become the most promising fields.