Background: The present study aimed to know the effects of age and measure the values ​​of parameters such as cholesterol, triglyceride, Hb, and PCV in patients with polycythemia vera. Methodology: a community sample of 56 males aged 30-59 years was studied, they were divided into 3 groups based on age, the first group from (30-39) years, the second group (40-49) years, and the third group (50-59) years. Blood was drawn from the venipuncture, as much as 5 mm from each patient. For hematological and biochemical parameters (Hb, PCV, Cho, and TG). Furthermore, the same previous analyses were conducted on 20 healthy people as a control group. Results: the hemoglobin value was non-significant (p>0.050) differences between the healthy subjects and the patients, while the PCV, Chol, and TG were significant (p<0.050) in patients' comparison to the healthy. Moreover, the results showed that age had no effect on the studied parameters among the groups, but there was a significant difference only between the age of patients and the healthy subjects between the groups. This study concluded that there was an increase in PCV, Chol, and TG significantly in patients with polycythemia vera, as the age did not affect the studied parameters.