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376024

Activation of human oocytes after previously intracytoplasmic sperm injection (ICSI) fertilization failure

Article

Last updated: 25 Dec 2024

Subjects

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Tags

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Abstract

         
          Infertility is a major problem that affects the individual and society. The current investigation aimed to investigate the efficiency of activation with ionomycin or 7% ethanol methods to assist oocyte for improving intracytoplasmic sperm injection (ICSI) outcomes in cases of recurrent failure of ICSI including severe male factor infertility, previous failure of fertilization and implantation. Both methods of assisted oocyte activation (AOA) used in this study recorded highly efficient implications on infertility duration, mature and fertilized oocytes, rates of fertilized, cleavage, blastocyst, embryo grades and pregnancy. It was found that using Ionomycin was preferable more than 7% Ethanol in patients' treatment with failure fertilization with ICSI.

DOI

10.21608/ajbs.2024.376024

Keywords

ICSI, AoA, Infertility, fertilization

Authors

First Name

Osama

Last Name

Badr

MiddleName

Mohamed

Affiliation

Animal Biotechnology Department, Genetic Engineering and Biotechnology Research Institute (GEBRI), University of Sadat City (USC)

Email

osama.badr@gebri.usc.edu.eg

City

Tanta -Gharbiya

Orcid

(0000-0003-0323-1130)

First Name

Mohamed

Last Name

Shehata

MiddleName

-

Affiliation

International Islamic Center for Population Studies and Research, Al-Azhar University

Email

-

City

-

Orcid

-

First Name

Eman

Last Name

Hassan

MiddleName

A.

Affiliation

International Islamic Center for Population Studies and Research, Al-Azhar University

Email

emannodcar@yahoo.com

City

-

Orcid

-

First Name

Hoda

Last Name

Gamal Alden

MiddleName

-

Affiliation

Animal Biotechnology Department, Genetic Engineering and Biotechnology Research Institute (GEBRI), University of Sadat City (USC)

Email

-

City

-

Orcid

-

Volume

20

Article Issue

2

Related Issue

48538

Issue Date

2024-06-01

Receive Date

2024-08-02

Publish Date

2024-06-25

Page Start

67

Page End

78

Print ISSN

1687-4870

Online ISSN

2314-5501

Link

https://ajbs.journals.ekb.eg/article_376024.html

Detail API

https://ajbs.journals.ekb.eg/service?article_code=376024

Order

376,024

Type

Original Article

Type Code

1,101

Publication Type

Journal

Publication Title

African Journal of Biological Sciences

Publication Link

https://ajbs.journals.ekb.eg/

MainTitle

Activation of human oocytes after previously intracytoplasmic sperm injection (ICSI) fertilization failure

Details

Type

Article

Created At

25 Dec 2024