The review article provides an in-depth collection of nutraceuticals in managing nausea and vomiting, particularly in chemotherapy-induced and postoperative cases (CINV and PONV). It explores the underlying mechanisms of these symptoms, focusing on disruptions in neurotransmitters such as serotonin, histamine, and dopamine. This comprehensive review highlights a global trend towards integrating plant-based extracts into conventional medicine, reflecting a growing preference for natural treatment alternatives. The article identifies various herbs and spices with antiemetic properties, including both traditional medicinal products and patented preparations. It examines the efficacy of vegetables and herbs from diverse medicinal systems worldwide, demonstrating their potential in preventing and treating nausea and vomiting. Additionally, the review outlines various screening methods and discusses current clinical studies, providing a thorough overview of the field. The article also reviews patents and marketed products related to active plants used as antiemetics, showcasing the commercial and practical applications of these natural remedies. The findings ultimately propose strategies for the nutraceutical industry to influence the medicinal benefits of foods, vegetables, and herbs as antiemetics. These strategies aim to cater to both local consumption and broader medicinal applications, highlighting the significant role of nutraceuticals in modern healthcare. The review emphasizes the importance of continued research and development in this area to enhance the effectiveness and accessibility of natural antiemetic treatments.