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348724

SKIN CANCER ADVANCED TOPICAL TREATMENT WITH IMIQUIMOD LOADED NANOCARRIERS: AN IN-DEPTH REVIEW

Article

Last updated: 04 Jan 2025

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Abstract

This review explores the significant advancements in topical skin cancer treatments, particularly focusing on the revolutionary role of nanotechnology in addressing the limitations found in traditional therapeutic methods. This comprehensive evaluation delves into the innovative development and clinical efficacy of cutting-edge nanocarrier platforms, notably those encapsulating Imiquimod. These platforms are specifically designed to enhance the delivery and performance of topical agents in the fight against nonmelanoma skin cancers, a prevalent concern in dermatological oncology.

The analysis methodically confronts the obstacles inherent to conventional skin cancer treatments by providing an in-depth examination of how nanotechnology-based platforms improve drug bioavailability, facilitate deeper skin penetration, and boost patient compliance with treatment protocols. This shift towards nanotechnology signifies a paradigm shift towards more patient-oriented and efficacious treatment modalities, offering a precise, targeted, and minimally invasive approach.

Moreover, the review not only underscoresillustrate the potential the transformative potential of nanotechnology in dermatological applications but alsoand heralds a significant progression in the field of topical oncological treatments field. By highlighting the advancements facilitated by nanocarrier systems.

This shows that, with such enhanced treatments of skin cancer, there shall be a shift from a patient-centered approach that minimizes interruptions to the regimen and hence reduces recurrence rates, which marks the first foremost goal. In this way, not only will more easily accessible and effective therapies be facilitated, but also, in proportion to a better quality of life, that is kept to the minimum of patient distress.

DOI

10.21608/bfsa.2024.276214.2058

Keywords

Imiquimod, skin cancer, basal cell carcinoma, Nanoplatform, Skin delivery system

Authors

First Name

Huda

Last Name

Abdel-Ghaffar

MiddleName

Mustafa

Affiliation

Central Administration of Drug Control, Egyptian Drug Authority, El Mansoria, Egypt

Email

dr.hudaabdelghaffar@gmail.com

City

El-Giza

Orcid

0009-0006-8112-8605

First Name

Hend

Last Name

Abdel-Bar

MiddleName

Mohamed

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, University of Sadat City, Sadat City, Egypt

Email

hend.abdelbaar@pharma.asu.edu.eg

City

Cairo

Orcid

0000-0001-5833-9267

First Name

Abdulaziz

Last Name

Al-mahallawi

MiddleName

Mohsen

Affiliation

Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt, School of Life and Medical Sciences, University of Hertfordshire Hosted by Global Academic Foundation, New Administrative Capital, Cairo, Egypt

Email

abdulaziz.mohsen@pharma.cu.edu.eg

City

Cairo

Orcid

0000-0003-1694-1342

First Name

Omaima

Last Name

El Gazayerly

MiddleName

Naim

Affiliation

Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Cairo University, Cairo, 11562, Egypt

Email

omaima.naim@pharma.cu.edu.eg

City

Cairo

Orcid

0000-0001-8475-0412

Volume

47

Article Issue

1

Related Issue

47734

Issue Date

2024-06-01

Receive Date

2024-03-11

Publish Date

2024-06-01

Page Start

119

Page End

140

Print ISSN

1110-0052

Online ISSN

3009-7703

Link

https://bpsa.journals.ekb.eg/article_348724.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=348724

Order

7

Type

Review Article

Type Code

2,839

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

SKIN CANCER ADVANCED TOPICAL TREATMENT WITH IMIQUIMOD LOADED NANOCARRIERS: AN IN-DEPTH REVIEW

Details

Type

Article

Created At

25 Dec 2024