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327337

CORRELATION BETWEEN HIGH SENSITIVITY C-REACTIVE PROTEIN AND LIPID PROFILE IN YOUNG PATIENTS WITH DIABETES MELLITUS TYPE 1 IN HOMS-SYRIA

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Last updated: 04 Jan 2025

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Abstract

In this study, we evaluated levels of high sensitivity C-reactive protein (hsCRP), as a predictor marker of cardiovascular disease, and  lipid profile and studied the relationship between them  in young patients with diabetes mellitus type 1 (DMT1). This study was conducted on 71 young with (DMT1), at Al-Arman Healthy Center in Homs- Syria, compared to 25 healthy controls at the same age. Blood samples were collected, and laboratory measurements were performed which included: HbA1c, FBG, TG, LDL-c, HDL-c, TC, hsCRP. Depending on the (HbA1c) values, all study patients had uncontrolled DM, and 58.5% of them had dyslipidemia. DMT1 patients had significantly higher serum concentrations of hsCRP, which indicates the presence of low-grade chronic inflammation. Significant positive correlation was found between (hsCRP) and (HbA1c, TG, LDL-c, TC), and a significant negative correlation with (HDL-c) in DMT 1 group. Conclusions, Atherosclerosis and vascular changes begin from an early age in DMT 1 patients with poor glycaemic control.

DOI

10.21608/bfsa.2023.327337

Keywords

Type 1 diabetes, Atherosclerosis, Cardiovascular disease, hsCRP

Authors

First Name

Reham

Last Name

Deeban

MiddleName

Naim

Affiliation

Department of Biochemistry and Microbiology, Al-Baath university, Homs, Syria

Email

rehamdeban93@gmail.com

City

-

Orcid

0000-0003-2988-5351

First Name

Sulaf

Last Name

Alwassouf

MiddleName

-

Affiliation

Department of Biochemistry and Microbiology, Al-Baath university, Homs, Syria

Email

sulafalwassouf@yahoo.com

City

-

Orcid

-

Volume

46

Article Issue

2

Related Issue

44483

Issue Date

2023-12-01

Receive Date

2023-02-10

Publish Date

2023-12-01

Page Start

1,077

Page End

1,084

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 46_Issue 2_Pages 1077-1084.pdf

PDF . 654.4kB

Link

https://bpsa.journals.ekb.eg/article_327337.html

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https://bpsa.journals.ekb.eg/service?article_code=327337

Order

327,337

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

CORRELATION BETWEEN HIGH SENSITIVITY C-REACTIVE PROTEIN AND LIPID PROFILE IN YOUNG PATIENTS WITH DIABETES MELLITUS TYPE 1 IN HOMS-SYRIA

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Type

Article

Created At

25 Dec 2024