ManageChatDiscover
327668

ADVANCES AND DEVELOPMENTS IN DRUG REPURPOSING; STATE OF ART

Article

Last updated: 04 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

Although the rapid progress in science and technology, developing new drugs from scratch has been expensive in recent decades. As a result, drug-repurposing, which implies seeking new utilizes for presently approved drugs instead of discovering new drug compounds, has emerged as a substitution tool to speed up the drug development procedure. Nowadays, drug repurposing accounts for 30% of newly approved drugs. With the explosive growth of pharmacological compounds' molecular, genomic, and phenotypic data, a novel area of drug repurposing called computational drug repurposing has emerged. This review provides an overview of recent progress in computational drug repurposing, including repositioning approaches, commonly used computational methods, validation techniques for repurposing studies, and the remaining encounters in computational repurposing. In this Review, we outline methods for drug repurposing (also known as drug repositioning), talk about difficulties encountered by the repurposing community, and suggest creative solutions to these issues. addressed to aid in maximising the benefits of medicinal repurposing.

DOI

10.21608/bfsa.2023.327668

Authors

First Name

Sarmad

Last Name

noori

MiddleName

dheyaa

Affiliation

Department of pharmaceutical chemistry- College of Pharmacy - Al-Ayen University

Email

sarmaddheyaa@gmail.com

City

-

Orcid

-

First Name

Mais

Last Name

Al-Hamdani

MiddleName

Mazin

Affiliation

Department of Pharmaceutics, College of Pharmacy , Al-Ayen University

Email

maismazinalhamdani@gmail.com

City

-

Orcid

-

First Name

Amira

Last Name

kassem

MiddleName

B

Affiliation

Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, Damnhour University Department of Clinical Pharmacy, Collage of Pharmacy, Al-Ayen University

Email

amira.kassem@pharm.dmu.eg

City

-

Orcid

-

Volume

46

Article Issue

2

Related Issue

44483

Issue Date

2023-12-01

Receive Date

2023-05-26

Publish Date

2023-12-01

Page Start

693

Page End

702

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 46_Issue 2_Pages 693-702.pdf

PDF . 724.3kB

Link

https://bpsa.journals.ekb.eg/article_327668.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=327668

Order

327,668

Type

Review Article

Type Code

2,839

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

ADVANCES AND DEVELOPMENTS IN DRUG REPURPOSING; STATE OF ART

Details

Type

Article

Created At

25 Dec 2024