Beta
ManageSearchChatDiscover
327344

SODIUM ALGINATE FILM INCORPORATED WITH ZINC OXIDE NANOPARTICLES AS ANTIBACTERIAL AGENT

Article

Last updated: 04 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

Alginate biopolymer has been used in the design and development of several wound dressing materials such as (foams, topical formulations, nanofibers, films) due to its favorable properties, such as biocompatibility and non-toxicity. It has been particularly attractive in wound healing applications to date. Additionally, it can be loaded by antibacterial materials such as antibiotics, antibacterial plant extracts and metal nano-oxides. The aim of this study was to design sodium alginate (SA) based zinc oxide (ZnO) nanoparticles as antibacterial film for wound healing applications. The ZnO nanoparticles, with an average particle size of about 16.75 nm, were synthesized by sol-gel method and characterized by scanning electron microscope (SEM) and Fourier-transform infrared spectroscopy (FTIR). They were then incorporated as antibacterial into sodium alginate with different concentration (0, 5, 7.5, 10%). Effectiveness of antibacterial activity was carried out against Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa) and Gram-positive bacteria (Staphylococcus aureus) to characterize the sample. The prepared ZnO/SA film presents a promising potential for applications as novel wound dressings

DOI

10.21608/bfsa.2023.327344

Keywords

Zinc Oxide Nanoparticles, Sodium alginate, sol-gel method, antibacterial film, wound dressing

Authors

First Name

Bashar

Last Name

Alshami

MiddleName

-

Affiliation

Department of Laboratory Diagnosis, Faculty of Pharmacy, Al-Baath University, Syria

Email

bshar.95@hotmail.com

City

-

Orcid

-

First Name

Wissam

Last Name

Zam

MiddleName

-

Affiliation

Department of Analytical and Food Chemistry, Faculty of Pharmacy, Tartous University, Syria

Email

ws.sarah2005@gmail.com

City

-

Orcid

0000-0002-2733-1884

First Name

Walid

Last Name

Khaddam

MiddleName

-

Affiliation

Department of Laboratory Diagnosis, Faculty of Pharmacy, Al-Baath University, Syria

Email

waleedkhaddam@gmail.com

City

-

Orcid

-

Volume

46

Article Issue

2

Related Issue

44483

Issue Date

2023-12-01

Receive Date

2023-02-18

Publish Date

2023-12-01

Page Start

683

Page End

692

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 46_Issue 2_Pages 683-692.pdf

PDF . 1.2MB

Link

https://bpsa.journals.ekb.eg/article_327344.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=327344

Order

327,344

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

SODIUM ALGINATE FILM INCORPORATED WITH ZINC OXIDE NANOPARTICLES AS ANTIBACTERIAL AGENT

Details

Type

Article

Created At

25 Dec 2024