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301182

INVESTIGATION OF THE PREVALENCE OF CANDIDURIA IN PATIENTS WITH HEMATOLOGIC MALIGNANCIES IN HOMS – SYRIA

Article

Last updated: 25 Dec 2024

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Abstract

The aim of this study was to investigate the incidence of candiduria in patients with hematologic malignancies, and identity its causative agents. The study included 100 patients with one of the following diseases: Acute myeloid leukemia (AML), Chronic myeloid leukemia (CML), Acute lymphoid leukemia (ALL), Chronic lymphoid leukemia (CLL), Multiple myeloma (MM), Hodgkin's lymphoma (HL) and Non-Hodgkin's lymphoma (NHL), who were admitted to the Hematology Department in some hospitals in Homs-Syria between December 2020 to September 2021. Candida species were identified by colony color on CHROMagar candida, germ tube production and micro-morphology on cornmeal agar. Among the 100 patients, 13 (13%) were positive for candiduria. C. albicans was the most common cause of candiduria (61.5%), followed by C. tropicalis and C. krusei (15.4%, respectively) and C. dubliniensis (7.7%). According to the results of the statistical analysis, candiduria was found to correlate significantly with female gender, previous exposure to a urinary catheter, acute myeloid leukemia (AML) and severe neutropenia (<500 cells/mm3).

DOI

10.21608/bfsa.2023.301182

Keywords

Candiduria, fungal infections, Hematologic malignancies, Opportunistic infections

Authors

First Name

Rafah

Last Name

Alali

MiddleName

-

Affiliation

Department of Biochemistry and Microbiology, Faculty of Pharmacy, Al-Baath University, Homs, Syria

Email

rafahali93@gmail.com

City

-

Orcid

-

First Name

Walid

Last Name

Khaddam

MiddleName

-

Affiliation

Department of Biochemistry and Microbiology, Faculty of Pharmacy, Al-Baath University, Homs, Syria

Email

waleedkhaddam@gmail.com

City

-

Orcid

-

First Name

Sundus

Last Name

Yaseen

MiddleName

-

Affiliation

Department of Biochemistry and Microbiology, Faculty of Pharmacy, Al-Kalamoon University, Deratiah, Syria

Email

sundus.alianabi@uok.edu.sy

City

-

Orcid

-

Volume

46

Article Issue

1

Related Issue

41495

Issue Date

2023-06-01

Receive Date

2022-08-14

Publish Date

2023-06-01

Page Start

465

Page End

472

Print ISSN

1110-0052

Online ISSN

3009-7703

Article File

BFSA_Volume 46_Issue 1_Pages 465-472.pdf

PDF . 706.4kB

Link

https://bpsa.journals.ekb.eg/article_301182.html

Detail API

https://bpsa.journals.ekb.eg/service?article_code=301182

Order

301,182

Type

Original Article

Type Code

1,096

Publication Type

Journal

Publication Title

Bulletin of Pharmaceutical Sciences Assiut University

Publication Link

https://bpsa.journals.ekb.eg/

MainTitle

INVESTIGATION OF THE PREVALENCE OF CANDIDURIA IN PATIENTS WITH HEMATOLOGIC MALIGNANCIES IN HOMS – SYRIA

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Type

Article

Created At

25 Dec 2024