Iron deficiency (ID) is the most prevalent underlying cause of anemia, accounting for half of all cases worldwide.  Therefore this study aimed to assess the ability of Pomegranate and Sugarcane molasses to treat iron deficiency anemia (IDA) that induced by high fiber diet (Cellulose) in rats. 40 female albino rats divided into eight groups (5 rats in each group): group 1 were fed on basal diet and served as control group, group 2 were fed on anemic diet and keep as anemic control group.  Group 3 were fed on anemic diet with 1% iron sulphate. Group 4 and group 5 were fed on diet group 3 with 5% and 10% sugarcane molasses, respectively .Group 6 and group 7 were fed on diet group 3 with 5% and 10% pomegranate molasses, respectively. Group 8 were fed on diet group 3 with 10 % mixed molasses (1:1). After one month. Nutritional, biological and hematologic evaluations of tested rat groups were estimated. The results indicated that high fiber diet induced a significant decrease in the Hb, Hct % and ferritin, while TIBC was increased. Complete blood count was affected by high fiber diet. But, a supplemented diet with pomegranate and sugarcane molasses reversed such changes and improved the anemic biomarkers. Moreover the best result was found in the group treated with pomegranate molasses followed by sugarcane molasses.