The purpose of this study was to examine ameliorating Effect of corn silk and forssk herb on renal functions of diabetic rats. The study involved 42 albino rats of the Sprague-Dawley strain. Following the adaptation period, all rats were randomly divided into two main groups. The first Main group was maintained on a basal diet and keept as a negative control group (-ve). The second main group (n = 35 rats) was injected subcutaneously with a single dose of streptozotocin to induce diabetes. Following streptozotocin administration, the rats were split into 5 groups. The First, a positive control group (+ve) fed on basal diet. The other four group were feed the experimental meals contained different percentages of corn silk extract (5% and10%), and forssk extract (5% and 10%), respectively. After six weeks of the experiment, the glucose levels were determined. Additionally, the biochemical functions of the liver and kidneys were established. As well as, MDA & SOD enzyme were created. The kidney and pancreas were examined histologically. The results indicated that five groups had lower liver enzyme levels of ALT, AST and ALP than the positive control group. In comparison to the positive control group, all examined groups had significant improvements in serum levels of glucose, urea nitrogen and creatinine. The results of histological investigations, which correlated with the biochemical study, significantly improved with the addition of corn silk and forssk. The study suggests that increasing corn silk and forssk consumption may be beneficial for diabetes patients, potentially acting as an anti-diabetic agent.