This research was conducted in order to investigate the potential effect of green coffee and white tea water extracts on the weight reduction of obese women. Eighty obese women (25-50 years old) with a BMI of 35- 39.9 was selected from Kasr Elainy Hospital, Cairo, Egypt. All obese women don't have any other diseases. All subjects were randomly classified into four groups. The 1st didn't receive any treatment, the 2nd treated with green coffee extract (GCE) twice a day, 3rd treated with white tea extract (WTE) twice a day, 4th treated with both (GCE & WTE) once a day of each. The phenolic content of both tested extracts was analyzed. Body mass index, waist/hip ratio, lipid profile, liver functions, kidney functions, leptin hormone, lipase, GSH and MDA were determined before and after the treatment period (8 weeks). After serum sample results indicated that obese subjects treated with GCE, WTE in groups 2,3 and 4 recorded an improvement in all tested parameters compared with obese subjects who hadn't received any treatment. According to the above results, green coffee as well as white tea water extracts may be used in the weight reduction of obese women and also may be useful for human beings.