لإhe aim of research was to investigate the effects of (silver or graphene) nanoparticles in concentrations of (0.0, 2.5, 5.0, 7.5 and 10.0) ppm/L drinking water in broiler chickens on some physical and chemical tibia bone measurements and some blood plasma parameters. For this purpose, 270 one day broiler chicks (Cobb 500) were randomly assigned to 9 experimental treatments (3replicates/ treatment, with 10/ chicks/replicate). In the end of experimental period (35 days) of age, tibia bone and blood plasma characteristics were determined. The results showed that: Tibia bone physical and chemical measurements weren't affected significantly by different types or levels of nanoparticles except organic matter%. There weren't significant differences between experimental treatments in all plasma total protein, Albumin, Globulin and A/G ratio related to nether types or levels of nanoparticles but, cholesterol, triglycerides and AST were differed significantly by types or levels of nanoparticles, however, ALT affected by different types of nanoparticles only. In addition, inclusion of different types or levels of nanoparticles in drinking water for broiler chickens didn't have any significant effects on tibia bone physical or chemical measurements and blood plasma parameters except tibia bone organic matter%, plasma cholesterol, triglycerides and AST.