Background: Sepsis is a severe healthcare problem that affects millions of people
worldwide every year, and it requires prompt management to reduce mortality.
So, early detection and appropriate sepsis management during the first few hours
improve outcomes. Aim: To evaluate the effect of implementing sepsis care
bundle on clinical outcomes of critically ill patients. Subjects and Method:
Study design: A quasi-experimental research design was utilized in this study.
Setting: This study was conducted at the Anesthesia Intensive Care Unit (ICU) in
Tanta Main University Hospitals and the surgical ICU in an International
Educational Hospital affiliated to Tanta University Hospitals. Subjects: A
purposive sample of 80 patients met the criteria for systemic inflammatory
response syndrome was selected. Tools: Tool (I): Critically Ill Patient
Assessment Sheet. Tool II: Critically Ill Patient's Clinical Outcomes Assessment.
Results: the study indicated statistically significant improvements in
physiological parameters and decreased the occurrence of septic shock, severe
sepsis, and multiple organ failure syndrome with P<0.05. Conclusion:
Implementing the sepsis care bundle for all critically ill sepsis cases can enhance
their clinical outcomes and reduce complications, particularly multiple organ
failure syndrome. Recommendations: The study should be replicated using large
probability samples in different settings to generalize the results.