Background: In intensive care units, nurses must eliminate distractions and interruptions to 
maintain efficient workflow while providing the highest level of care for critically ill patients 
with life-threatening conditions. Aim: To assess the relation between workflow interruption 
and nurses‘ work functioning at intensive care units. Subjects and Method: Research design:
A descriptive correlational research design was utilized to conduct this study. Setting: The 
study's was conducted at Tanta Main University, Emergency, Medical, Pediatric, Chest, and 
Ophthalmology Hospitals. Subjects: The study's subjects consisted of a stratified random 
sample of nurses (n=378). Tools: Two tools were used to collect the data: Workflow 
Interruption Structured and Nurses Work Functioning Structured Questionnaire. Results:
Showed that the majority (89.2%) of nurses had a moderate interruption level the vast majority 
(91.5%) of nurses had a low level of work functioning, and a minor percent of them had 
moderate level of work functioning. Conclusion: showed that there was a negative statistically 
significant correlation between workflow interruption and nurses' work functioning.
Recommendation: for hospital administration, needs to invest in dependable medical 
equipment and set up procedures for regular maintenance and repair to minimize disruptions 
from technical issues.