Background: Exercise-based cardiac rehabilitation has been found to improve patient-reported 
outcome measures and would be beneficial after heart valve surgery. Aim: Evaluate effect of 
exercise protocol on patients undergoing heart valve surgery -reported outcomes measures. 
Patients and methods: Research design: A quasi-experimental research design (study/control) 
was utilized. Sample: A purposeful sample of sixty patients undergoing heart valve surgery from 
both sexes, patients were randomly assigned into two equal groups. Setting: Cardiothoracic 
surgery department and outpatient clinic in Assiut University Heart Hospital. Tools: A structured 
interview questionnaire, Heart QoL questionnaire and Edmonton Symptom Assessment System 
(ESAS-r). Results: High statistically significance (p value <0.001**)  was found in the study's 
findings between study and control group patients in global score of heart QOL after one month 
(24.83±2&18.33±2.93 respectively) also after three months (41.2±1.42 &32.03±2.8693 
respectively). Patients in the study group and those in the control group showed highly 
significantly difference from one another in terms of overall score of Edmonton Symptom 
Assessment System after one month of exercise protocol (48.3±7.05 56.67±6.1 respectively) and 
after three months (8.07±8.25 &15.17±6.64 respectively) with p value (<0.001**). Conclusion: 
The study's results elucidated that exercise protocol improved patients reported outcomes 
measures as quality of life and symptoms in study group patients in comparison with control 
group patients. Recommendations: Comprehensive Arabic guidebook about exercise training 
through perioperative valve surgery should be easy to access by patients to help in improvement 
in patient reported outcome measures.