Background: Children with congenital heart diseases face serious problems which affect the
quality of their life so; promoting mothers' self-efficacy may affect quality of life of their children
with congenital heart disease. The study aimed to evaluate the effect of educational instructions
on mothers' self-efficacy regarding quality of life their children with congenital heart diseases.
Design: A quasi- experimental research design was used in the present study; the study was
conducted at inpatient and outpatient Pediatric Department of Tanta Main University Hospital
which affiliated to Ministry of Higher Education and scientific Research and Kafer El-Shiek Main
University Hospitals. Subjects and Method: a purposive sample of seventy children and their
mothers were involved in the present study the children aged from six to twelve years old. Three
Tools were used: Mothers' knowledge structured questionnaire, the children's quality of life scale
and the mothers' self-efficacy scale. The results revealed that mothers' knowledge had improved
after the educational instructions implementation with positive correlation between total mothers
knowledge about congenital heart diseases and their self-efficacy which in turn improve the quality
of life of their children. The study concluded that the educational instructions had great effect in
improving mothers' knowledge, self-efficacy and quality of life of their children with congenital
heart diseases. The study recommended that periodical educational program should be conducted
for nurses to be knowledgeable about congenital heart diseases and nursing caring of these
children