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397679

STUDIES ON CHRONIC HEPATITIS: 1- LIPID PROFILE OF CHRONIC C HEPATITIS AFFECTED PATIENTS WITH SPECIAL REFERENCES TO SERUM TRACE ELEMENTS

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Last updated: 24 Dec 2024

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Abstract

This study was conducted on 50 male subjects with an age rang­ing 31 to 54 years with mean of 43.6 ± 8.1, divided into two groups: group one included 30 male subjects with the diagnosis of chronic hepa­titis C, and group two included 20 age matched normal volunteers. Both groups were subjected to clinical examination, liver functions, abdominal sonography, polyrnorase chain reaction (PCR) for Hepatitis C virus (FICV), determination o/ serum iron, zinc. copper, and magnesium, lipoprotein profile. In addition patients, group were subjected to liver biopsy and es­timation of histology activity index. Results showed no significant differ­ence between patients mean serum iron (129.2 ± 41 ug/ dl) and control (101.45 ± 33.5 ug/c11) 'P < 0,269'; between patients mean serum cop­per (105.4 = 27_6 ug/dI) and control (104.95 ± 24.29 ugf dl) P < 0.359", between patients mean serum zinc level (140.6 ± 12.6 ug(dl) and control (137.63 ± 14.06 ug/dI) P < 0.347", between patients mean serum magnesium (20.817 ± 2.924 ug/dI) and control (21.66 ± 2.33 ugid1): P = 0,24". Lipoprotein profile showed no significant differ­ence between serum cholesterol. triglycerides, LDL, HDL in both groups_ We found elevated serum iron in 6 patients (20%), elevated serum cop­per in 5 patients (16.7%) and elevated serum magnesium in two pa­tients (6.7%) in diseased group. Only HDL showed significant positive correlation with histological activity index (Pe 0.01)_ in conclusion, there is no correlation between studied serum trace elements and severity of chronic hepatitis.

DOI

10.21608/ejar.2001.397679

Keywords

Hepatitis. Nutrition, Lipid profile, and trace elements

Authors

First Name

MOSTAFA M. H.

Last Name

OSFOR

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Affiliation

National Research Centre, Egypt

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Orcid

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First Name

AMR M.

Last Name

ABDEL-WAHAB

MiddleName

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Affiliation

Faculty of Agriculture, El-Minia University, Egypt

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Orcid

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First Name

HISHAM

Last Name

METAWA

MiddleName

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Affiliation

National Research Centre, Egypt

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City

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Orcid

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First Name

MAHMOUD S. S.

Last Name

ARBID

MiddleName

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Affiliation

National Research Centre, Egypt

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Orcid

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First Name

AHMED

Last Name

TAWFIK

MiddleName

-

Affiliation

Animal Health Research institute, Agricultural Research Centre, Dokki, Giza, Egypt

Email

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Orcid

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Volume

79

Article Issue

1

Related Issue

51967

Issue Date

2001-03-01

Receive Date

2000-12-01

Publish Date

2001-03-31

Page Start

309

Page End

318

Print ISSN

1110-6336

Online ISSN

2812-4936

Article File

EJAR_Volume 79_Issue 1_Pages 309-318.pdf

PDF . 2.8MB

Link

https://ejar.journals.ekb.eg/article_397679.html

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https://ejar.journals.ekb.eg/service?article_code=397679

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Original Article

Type Code

1,041

Publication Type

Journal

Publication Title

Egyptian Journal of Agricultural Research

Publication Link

https://ejar.journals.ekb.eg/

MainTitle

STUDIES ON CHRONIC HEPATITIS: 1- LIPID PROFILE OF CHRONIC C HEPATITIS AFFECTED PATIENTS WITH SPECIAL REFERENCES TO SERUM TRACE ELEMENTS

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Article

Created At

24 Dec 2024