A breeding program for screening and developing wheat lines re­sistant to aphid was conduted at ARC since 1986. Crosses were made between the two translocation lines each possessing a segment of a chromosome from the rye variety Insave x Giza 157, Sakha 61 and Sak­ha 69. Backcrossing was continued up to BC3/BC4. Individual plant se­lection based on resistance/tolerance to R.padi the most destructive aphid in Egypt, and desirable plant phenotype was followed. Each of the selected plants phenotype was followed. Each of the selected plants was grown in one row and selection was practiced within and among rows. Visually superior lines resistant/tolerant to aphids were included in yield trails for aphid screening and yield evaluation from 1991 and through 1996. Eight lines possessing varying degress of aphid resistance were experimented in two verification, two large and two small yield trials consisting of 11, 27 and 42 lines, respectively. The recurrent varieties Sakha 69 and Giza 164 were used as control in each experiment. Two fairly resistant lines to R.padi, exhibited grain yield to the recurrent, two moderate and 3 tolerant lines exhibited grain yield significantly two mod­erate and 3 tolerant lines exhibited grain yield significantly increased over the recurrent were achieved from the verification trials. these lines will be handed over to the Wheat Res. Section to be experimented in 11 location allover the country and for seed multiplication. Results from small and large trials will be confirmed in the coming seasons. These results positively assume that various levels of resis­tance can be combined with high grain yield and breeding for aphid resis­tance/tolerance can be achieved. Another phase of this program has been initiated using the re­sistant amphiploids Amigo, Largo and Shandawell 1 (produced in this work) x Giza 160, 163 and 164. A total of 720 lines selected from BC2 were subjected to artificial infestation with aphids in the greenhouse and natural infestation of R.padi in the field. Six lines (Largo x Giza 160) and 6 lines (Amigo x Giza 164) proved to be resistant to S.graminum under greenhouse conditions. An excess of resistant lines was obtained under field conditions against R.padi because infestation was light.