In the cotton season of 1997, EI-Behira Governorate, Kafr El-Dawar District, in 518 cotton feddans, Gossyplure (the sex pheromone of the pink bollworm (PBW), Pectionophora gossypiella Saunders was used in three different formulations (Lastfly, P.B. Rope and Selibate) in three different dosages (according to three different plant triggers and three different insect triggers) in two different applications against the 1st and the 3rd generations of the PBW. Three different insecticide ap‌plications (from different chemical groups), in differnt dosages were used against the two cotton leafworm, Spodoptera littoralis Boised (CLW) generations on cotton (Baona and Mesra generations), and in the mainwhile against the 2nd and 4th generations of the PBW. There was no significant difference (LSD0.05 = 5.64) in the boll infestation per‌centages when different pheromone and insecticide dosages were used against different plant and insect triggers. When 1/3 pheromone dosage was used against the tow (13) plant and insect triggers (cotton nodes or/and PBW male moths/trap/night), the boll infestation mean was 8.21%. When 1/2 pheromone dosage was used against the intermediate (4-7) plant and insect triggers (cotton nodes and/or PBW male moths/ trap/night), the boll infestation mean was 3.4%, while when a full dos‌age pheromone application was used against the high (28) plant and in‌sect triggers (cotton nodes and/or PBW male moths/trap/night), the boll infestation mean was 3.63%. These results indicated the importance of using PBW pheromone disruption applications and insecticides against PBW and CLW on the following bases: 1.Using 1/3 pheromone dosage against the low (13) plant and insect triggers. 2.Using 1/2 pheromone dosage against the intermediate (4-7) plant and insect triggers. 3.Using a full dosage pheromone application against the high (28) plant and insect triggers. 4.Using two different pheromone applications against the 1st and 3rd PBW generations in cotton_ 5.Using two different insecticide applications against the 2nd and the 4th PBW generations and in the mainwhile against and two CLW gener-ations (in Mesra ands Baona).