Eighteen fungi were isolated from peanut seeds (Arachis hypogea L). Fusarium oxysporum, Fused= solani, Sclerotiurn rolfsii, Macrophomi­na phaseolina and Rhizoctonia solani were the most frequently isolated fungi and had the highest percentages of incidence. During the two sea­sons of 1995 and 1996, five fungicides were tested against root rot and wilt of peanut, as seed dressing and soil treatments. Rizolex T 50% was the best fungicide in reducing disease infection in both seasons, un­der greenhouse and field experiments, followed by soil treatment with chlorotosep and Amconil. The lowest total yields were obtained with Topsin M which was the least efficient in reducing the percentage of dis­ease infection in peanut seedling. Moreover, Vitavax Thiram and Rizolex T were the more efficient to reduce the percentage of pod rot infection against all the tested isolates under both artificial and natural infections.