Ten parasite tree dogs were grouped into 2 groups: Group I, a negative control and Group II, infected with 5000 T.spiralis larvae / each dog. Trichinella spiralis infected dogs under study became off food, and diarrhoeic by the 2311 up to the 7111 day post-infection. Vomiting has been observed in one of the infected dogs. Fe‌ver was recorded on the 2nd up to the 2151 day post-infection. The main blood changes were significant decrease in haemoglo‌bin concentration (7th — 2151 days PI) and mean corpuscular haemoglo‌bin concentration (MCHC) by the 711t day P.I. together with a significant increase in total eosinophil and leukocyte counts (4111— 2191 daysPt). Serum biochemical alterations were detected on the 71h day up to the 281h day P.I. (end of experiment) depending on the test used. Serum biochemical changes included a significant decrease in total ser‌um proteins, albumin, urea and creatinine concentrations, together with increased serum globulin concentration and serum ALT activity levels. It could be concluded that, blood and serum diagnostic indices are supplementary tests during vague trichinosis symptoms.