To evaluate the initial and bio-residual efficacy of Bancol on Schis­tocerca gregaria(Froskal), the last nymphal stadium were fed with 100 ppm on the 2nd-3rd day after moulting to analysis fat body and haemo­lymph on day 6. Two days before eclosion and on day 5 after final ecdy­sis a basic metabolism that affected Bancol treatment which are gener­ated in the central nervous system was established. Derived a cessation of some metabolism in nymphs such as car­bohydrates, protein, lipid and cholesterol. This is due to decrease of tri­glycerides reaching 56.82% and 80.28% for alkaline phosphatase. Re­flectional, decreased the amount of food intake by 53.26% and pellets 49.32% besides 45.55% mortality in 5th instar. The change is due to in­terference with the central nervous system rather than to the altered feeding behaviour. Thus, the mortality of adult was 100% at 5th day old in spite of increase of metabolism in fat body (site of synthesis), but did no uptake to haemolymph. This is due to decrease of alkaline phospha­tase reaching 85.03% and the enzyme of transaminase it was 77.93%. Consequently, it could be recommended to use the Bancot in frame of an integrated pest management system.