Water stress in Egypt is expected to further increase in the future as a result of climate change and rapid population growth that impact of crop production and soil properties. To evaluate and reduce the impact of water stress, two field experiments were conducted at Shandaweel Agricultural Research Station, Sohag Governorate, Egypt in 2020/2021 and 2021/2022 seasons under normal irrigation and water stress and different rates of K-fertilization combined with silicate and chitosan addition. The sugarcane cultivar (Giza-4) “Saccharum sp L." was applied as a planting material. A randomized complete block design (RCBD) was used as a split-split plot arrangement with three replicated. The results explained that water stress had a significant effect on all studied traits of sugarcane. Normal irrigation improved height, diameter stalk, number of millable canes/fed, brix%, sucrose% and sugar recovery% as well as cane and sugar yields/fed in both seasons. Moreover, increasing K-level to 48 kg K₂O/fed resulted in a significant increase in all studied traits of sugarcane in both seasons. As well as the results indicated that the application of silicone + nano chitosan had positive effects on height and diameter stalk, number of millable canes/fed, brix%, sucrose% and sugar recovery% as well as cane and sugar yields/fed in both seasons reached to 90.2% under water stress compared with the production under normal irrigation. In addition, soil salinity (EC) and soil pH were generally decrease with treatments application meanwhile all other soil studied parameters (cations, anions and available NPK) were increase compared with control. Thus, it was found that, supplying sugarcane with a combination of both 48 kg K₂O/fed and (silicon + nano chitosan) application can be recommended to adapt and reduce the negative impact of water stress on soil and crop production and get the economical cane and sugar yields, as well as the best quality traits of sugarcane crop.