The present study was carried out at El-Mattana Agricultural Re­search Station, Qena Governorate, Upper Egypt in 2000/2001 and 2001/2002 growing seasons to evaluate four sugarcane varieties (three promising ones viz. F.160, Ph.8013 and G.85-37 and the commercial va­riety G.T.54-9) grown at two seed rates of 12600 and 16800 cuttings of 3-budded cane cuttings, i.e., 37800 and 50400 buds/fed, respective­ly, to obtain maximum cane and sugar yields. A split-plot experimental design with three replications was used in this work, where the main plots were assigned for sugarcane varieties while the seed rates were distributed in the sub-plots. The results indicated that the tested sugarcane varieties signifi­cantly differed in stalk diameter and sucrose percentage (in both sea­sons) as well as stalk height and number of millable cane/m² (in the 2^nd season). However, no statistical variances were detected among varie­ties in juice purity percentage, cane and sugar yields/fed in both sea­sons. Planting sugarcane using 16800 cane setts/fed two drills at­tained significantly higher number of minable stalks/m², cane and sugar yields compared with 12600 cuttings/fed in both seasons. Higher values of stalk height, number of millable cane/m² and purity percentage were significantly obtained by planting 2.0 drills in the 2nd season. On the contrary, thicker stalks were produced in case of using 16800 cane setts/fed in both seasons. The interaction between the studied factors had no marked ef­fect on stalk diameter, number of millable cane/m² and sucrose percent­age in both seasons. Meanwhile, stalk height and purity percentage were significantly affected by the interaction (in the 1^st season) as well as cane and sugar yields (in the 2^nd season).