Background: Conversation map is an innovative education method has been used to facilitate education for patients with type 2 diabetes. Aim: To assess the effect of interactive conversation map on self-management, self-efficacy, and psychological distress for patients with type 2 Diabetes. Research design: a quasi-experimental study was conducted with pre, post and follow-up.Setting: The current study was recruited at Diabetic and endocrine outpatient's clinic at Al Kaser Al Ani Hospital, affiliated to Cairo university, Cairo, Egypt. Subjects: Participants were selected by convenient sampling consisted of 340 adults' patients from both gender with type 2 diabetes. Tools for data collection: Five tools were used for data collection I. Structured interview questionnaire consists of 1. Patient demographic characteristics as, age, gender, education level, and occupation). 2. Patient medicalhistory. 3. Patient knowledge regarding diabetes millets. II. Diabetes self-management questionnaire, III. Diabetes management self-efficacy scale (DMSES). IV. The diabetes distress scale (DDS), V. The world Health organization -5 well-being index (WHO-5).  Result: The finding of the study concluded that type 2 diabetic patients who receive educational program via interactive conversation map had improvement in level of knowledge, self-management, diabetes self-efficacy, and wellbeing. In addition, decreasing psychological distress Conclusion: Interactive conversation maps have a positive effect in improving patient level of knowledge, enhancing self-management, improving self-efficacy, lowering psychological distress, and improving well-being for type 2 diabetic patients.  Recommendation: Healthcare providers should consider incorporating interactive conversation map into diabetes education to optimize   self-management, self-efficacy and decreasing psychological distress for patients with Type 2 Diabetes.