Background: Patient knowledge regarding pneumonia plays a vital role in treatment adherence, empowerment, self-management, anxiety reduction, communication, quality of life, disease management and health literacy. Aim: Assess patient information regarding pneumonia and providing comprehensive nursing intervention. Research design: A descriptive research design was used to achieve the aim of this study. Subjects: One hundred thirty two adult male and female patients, from 18 to less than their ages ranged or equal to 65 years. Setting: This study was conducted inpatient in chest hospital at Assiut city. Tool: Interview questionnaire included demographic, medical and questions regarding patient's knowledge assessment. Results: 73.5% the studied group were 55 to ≤ 65yrs old, regarding to gender 59.8% of the studied sample were female. (97.0%) of studied sample had shortness of breathing, hypertension in(50%) and abnormal chest x-ray in (74.2%).Conclusion: It was concluded that the majority of patients had poor information level regarding pneumonia and they were statistical significance different between educational level and level of information, occupation and patient information. Recommendations: A tailored intervention program designed and implemented to increase the knowledge about pneumonia.