Background: Language skills, retained information, and organizational abilities are the main areas impacted by dyslexia, which has been identified as a neurological problem. Studies on children with dyslexia have shown that socio-emotional support intervention reduces anxiety and boosts self-esteem. Aim: The current study aimed to investigate the effectiveness of socio- emotional support intervention in reducing anxiety and improving self-esteem among dyslexic children. Research design: To meet the goal of this study, a quasi-experimental research methodology was employed (pre and post-intervention). Subjects: A purposive sample was utilized in the study consisted of 40 dyslexic children (pre and post-test). Tools: Structured interview questionnaire, Screen for Child Anxiety Related Emotional Disorders and Hare self-esteem scale. Results: The current results showed that less than three-quarters of the children have an indication of anxiety disorder presence at the pretest, while it decreased to be just (15%) at the post-test. There was a highly significant difference between the pre and post-test as regarding to Hare Self-Esteem subscales' levels. Conclusion: there was a negative significant correlation between the Child Anxiety disorder and all Hare Self-Esteem subscales' levels. Recommendations: Research on comparative effectiveness might help in determining the best intervention strategies that promote evidence-based practices.