Background: Clinical Pathways aim to advance the quality, co-ordination, and continuousness of care for the patient with chest trauma across changed areas. Aim: The study aimed to evaluate effect of implementing of the clinical pathway on chest trauma patients out comes. Design: A quasi-experimental research design applied in this study. Subject: Contained 60 adult patients with chest trauma, similarly, divided into study and control group. Setting: The study conducted at the trauma intensive care unit at Assiut University Hospital. Tools: Four tools were used: Tool 1: Chest trauma assessment sheet, Tool 2: Patient's clinical pathway variances checklist, Tool 3: (pain, inspiration, and cough) score scale and Tool 4: Chest trauma patients' outcomes assessment sheet. Result: the current study findings showed that regards sequential organ failure assessment score. with more patients in the study group have low score of mortality rate (96.7 %), and a larger section of patients in the control group moderate score of mortality rate (40.0%). So that, differences in this Score between groups were statistically significant. Also, PIC score between control and study group were statistically significant difference. Conclusions: Implementation of clinical pathway impact positively on patients' outcomes. That reflected by high positive correlation among study and control group related to prolonged duration of intensive care unit stay and duration of mechanical ventilation. Recommendation: Further research is needed to confirm these findings across multiple centers and patient populations. Continuous training for healthcare providers involved in chest trauma care are essential for consistent adherence to the pathway.