Background: Paternalistic leadership is style of leadership that leader merges strict system with the empathy of a paternal figure and moral character in a personalized climate that empower nurses accomplish more excellently and proficiently and assistance nurses to condense cynical behavior to hospital and improve pride feeling. Aim: Examine paternalistic leadership, organizational cynicism and its relation with organizational pride at Main Mansoura University Hospital. Method: Descriptive correlational design utilized as well as the study was done on 180 staff nurses working at all inpatient units. Used three tools for collect data; Paternalistic Leadership Questionnaire, Organizational Cynicism Questionnaire and Organizational Pride Questionnaire. Results: Highly statistically significant relationship among paternalistic leadership and overall items of organizational pride excepting managerially authoritarian dimension was no statistically significant. As well as, negative statistically significant relationship amongst organizational cynicism and overall items of organizational pride. In addition, 87.8% and 70.6 of nurses' apparent moderate level of paternalistic leadership and organizational cynicism, while, 66.1% of them reported high level of organizational pride. Conclusion: Paternalistic leadership style improves organizational pride and organizational pride decrease organizational cynicism. Recommendations: Establishing stress management and emotional intelligence training programs for nurses in reducing hospital cynicism and ultimately improved organizational pride.