Abstract Background: Patients undergoing coronary angiography; have various needs such as physical, psychological, and social needs. Aim: To determine the information needs of patients undergoing coronary angiography. Research question: What is information needed for patients undergoing coronary angiography? Research design: A descriptive research design was utilized to conduct this study. Subjects: A convenience sample included all admitted patients for coronary angiography at Assiut University Heart Hospital for six months; the total number of subjects was 140 adult male and female. Setting: The present study was conducted in the cardiology department at Assiut University Heart Hospital. Tool: Interview patients' assessment sheet included demographic, medical data, and patient knowledge assessment. Results: The highest percentage of studied patients is the unsatisfactory level of knowledge about coronary angiography (80.7%). There is a statistically significant difference between education level and patient knowledge (p =.034). Conclusion: Patients undergoing coronary angiography had an unsatisfactory level of knowledge regarding the disease process and coronary angiography procedure. Recommendation: Provide nursing instructions for patients before, during, and after coronary angiography procedure and educational booklet should be provided for patients with needed instructions and knowledge about coronary angiography.