Gynecological cancers, the fourth most prevalent type of cancer overall, are a serious public health issue because they put older women at higher risk for deaths and illness. Gynecological tumors can be prevented and treated when detected early, just like many other cancer kinds. The study aimed to: Assessing elderly women's knowledge, practice and attitude toward the prevention of gynecological cancer. Subjects and Method: It were conducted using a descriptive research design. This study was carried out at the Gynecological department, cancer department, and outpatient clinics for gynecology at Sohag university hospitals. There were 200 senior people in the entire sample. Tools: Four tools were used. Tool I: There were three tools employed. Structured interview questionnaire is the first tool. Socio-demographic details, medical history, and obstetric and gynecological details are all included. Tool II: Gynecological cancer prevention information scale (GCPIs). Tool III: Attitude toward Gynecological cancer prevention. Tool IV: Practice toward Gynecological Cancer Prevention. Results: The study revealed that further than half (61.5%) of the older women participants had negative attitudes towards GCP, and the majority of them (87.0%, 94.0%) had low knowledge and practice levels respectively. Conclusion: There were Pearson correlation coefficients and statistically significant differences between elderly knowledge and practice level, as well as between elderly attitude and practice level (P<0.001**). Recommendations: Offering senior women with a health education program about gynecological cancer prevention, management, and rehabilitation is advised