Background: Diabetic peripheral neuropathy is a chronic microvascular complication of diabetes which can lead tofoot ulcers, amputations, and mortality. Based on the current evidence-based practice; providing a care bundle can improve patient outcome. So, this study aimed to evaluate the effect of a nursing care bundle on severity of diabetic peripheral neuropathy. Methods/Design: Quasi-experimental single group pre- posttest design was utilized. A purposive sample of sixty-two diabetic attendees (new and established patients) to the Center of diabetes & endocrinology at Assiut University Hospital had been assessed at baseline using the following tools: Patient assessment sheet, Diabetic Self Care Knowledge Questionnaire (DSCK30Q), and Clinical neurological examination (CNE) scale. Then after receiving a care bundle, participant had been reassessed after three months later. Results: revealed that there was no statistically significant difference between baseline and follow-up measurements regarding neuropathy stage. Moreover, there was a highly statistically significant improvement in tested variables after receiving a care bundle with P-value <0.01. HgbA1c level was 10.56 (2.83) at baseline, while it was 8.83(1.75) at follow-up. The mean of total diabetic self-care knowledge was 10.43 (3.71) at baseline, while it was 20.93(4.76) at follow-up. Regarding neuropathy severity; (88.7%) have mild level at baseline, while (91.9%) have at follow-up. Conclusion/Recommendation: Diabetic peripheral neuropathy care bundle led to a targeted positive outcome as it maintained on the stage of diabetic peripheral neuropathy and didn't progress to the next stage. Also, severity of symptoms had been decreased in some patients/Diabetic peripheral neuropathy care bundle should be an integral part of diabetes care.