Background: Postpartum low back pain (PLBP) is a prominent health problem which commonly affects women worldwide. About 30 to 78 percent of women experience LBP, which is considered a prevalent musculoskeletal problem during pregnancy and its relieve post-delivery is very slow and often incomplete. Aim: of the study: to evaluate the effect of kinesio tape on postpartum low back pain and functional disability in women after cesarean section. Design: A quasi-experimental research design (non-equivalent control group pre-test post-test design) was utilized. Subjects: A purposive sample of 80 post-cesarean women. Setting: the outpatient obstetrics and gynecologic department of Mansoura University Hospital, Dakahlia Governorate, Egypt. Tools: Data was collected through three tools, basic data Structured Interview Questionnaire, Numerical Pain Rating Scale, and Roland-Morris Dysfunction Questionnaire. Results: the mean of low-back pain intensity decreased to 6.45±1.13 in the study group compared to7.42±1.10 in the control group 3 days after intervention and to 3.17±1.31 in the study group compared to 4.82±1.17 in the control group 7 days after intervention. In addition, the mean of functional disability was noticed in the study group to become 3.77±0.83 while it is 8.40±0.84 in the control group 7 days after intervention. Conclusion: Kinesio tape (KT) significantly improves low back pain during postpartum period and enhances women's functional abilities. Recommendations: It is suggested that maternity nurses should encourage the use of Kinesio tape for postpartum low back pain