Background: High quality Patients care can achieve only through accurate and concise transfer of patient data, information through SBAR format to ensure patient's safety Aim: Research aim to assess the effect of SBAR inservices training program on patient's safety. Research design: A quasi-experimental research design. Setting: the present study was performed at Sohag Cancer Center. Subject: Consisted of 50 nurse's works at inpatients department. Tools: consist of I): SBAR knowledge questionnaire which containing:- Part I: Personal data sheet. Part II: Situation, Background, Assessment, and Recommendation sheet. II): Patient's safety audit checklist. III): SBAR practice observational checklist. Results: The study illustrated that the highest percentage of nurses had unsatisfactory knowledge score for three items, in pre-program phase but satisfactory, in immediate post while decline in follow-up phase to be (92%, 94%, 94%) (100%, 100%, 100%) (80%, 100%, 82%) respectively. The highest percentage of nurses had inadequate performance in pre-program phase but adequate in immediate post and follow-up phase, with no activities (25) of patient's safety in pre-program phase but established activity in immediate post(65) and follow-up(61) phase. Conclusion: There are significant statistical improvements of nurses′ knowledge and practice of SBAR shift report for nurses in the immediate post and follow-up phase, with significant improvements in patients' safety. Recommendations: Supervising nurses to ensure application of SBAR format, and Add SBAR format to Nursing Administration course curriculum at nursing faculty.