Abstract: Background: Psycho-physiological care during the third stage of labor including breast crawl technique comprises immediate and continued mother and baby skin-to-skin contact as well as breastfeeding. It has been believed to bring numerous protective effects for the mother and her newborn. Aim of the study: This study aimed to evaluate the effect of breast crawl on the third stage of labor, initiation of breastfeeding, and bonding among primiparae. Design: A quasi-experimental research design was utilized. Subjects: A convenient sample of 60 primipara women. Setting: labor and delivery unit of Damnhour Medical National Institute, Egypt. Tools: Data was collected through four tools, basic data structured interview questionnaire, clinical assessment sheet, modified LATCH scale, and postpartum bonding questionnaire. Results: This study revealed significantly decreased mean of blood loss (312.67 ± 51.154 ml) after delivery and short duration of the 3rd stage of labor (12.75 ± 4.858 min) among the study group, compared to (357.50 ± 43.127 ml & 20.25 ± 5.217 min) respectively of the control group. In addition, the study revealed a significantly higher total score of breastfeeding initiation and bonding among 80% & 90% respectively of the study group, compared to 0% &10% respectively of the control group. Conclusion: This study concluded that breast crawl significantly reduced the amount of blood loss after delivery, shortened the duration of the 3rd stage of labor, enhanced good breastfeeding initiation and strong bonding. Recommendations: It is suggested that maternity nurses should support evidence-based breast crawl practice during the 3rd stage of labor.