Plant-parasitic nematodes are a taxonomic assemblage of microorganisms classified within the phylum Nematoda that are characterized by their round, worm-like morphology, and their ability to derive sustenance from the live cells of plants. They are responsible for causing harm resulting in economic losses for nearly all cultivated plants on a global scale. The global economic impact of plant-parasitic nematode infection has been estimated at 30 billion USD. A variety of strategies were employed in the management of plant-parasitic nematode infestation. One of the methods that has demonstrated efficacy in managing phytonematodes is the use of nematicides. However, it is worth noting that in recent years, the utilization of these substances has been limited due to their adverse impacts on both the environment and human health. There exist alternate techniques, in addition to or in lieu of nematicides, that show promise in the management of plant-parasitic nematodes. The utilization of nanotechnology-based approaches represents a cost-effective and environmentally sustainable alternative for managing agricultural nematodes and pests. This paper provides a comprehensive overview of several techniques employed for the manufacture of nanoparticles. Additionally, it examines the impact of nanoparticles on phytonematodes and plants, as well as the merits and drawbacks associated with the utilization of nanoparticles for the management of plant diseases.